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排序方式: 共有1200条查询结果,搜索用时 31 毫秒
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Syed Mohammed Basheeruddin Asdaq Obulesu Challa Abdulhakeem S. Alamri Walaa F. Alsanie Majid Alhomrani Abdulrahman Hadi Almutiri Majed Sadun Alshammari 《Molecules (Basel, Switzerland)》2021,26(11)
This study was conducted to determine the potential interaction of aged garlic extract (AGE) with carvedilol (CAR), as well as to investigate the role of S-allyl-l-cysteine (SAC), an active constituent of AGE, in rats with isoproterenol (ISO)-induced myocardial dysfunction. At the end of three weeks of treatment with AGE (2 and 5 mL/kg) or SAC (13.1 and 32.76 mg/kg), either alone or along with CAR (10 mg/kg) in the respective groups of animals, ISO was administered subcutaneously to induce myocardial damage. Myocardial infarction (MI) diagnostic predictor enzymes, lactate dehydrogenase (LDH) and creatinine kinase (CK-MB), were measured in both serum and heart tissue homogenates (HTH). Superoxide dismutase (SOD), catalase, and thiobarbituric acid reactive species (TBARS) were estimated in HTH. When compared with other groups, the combined therapy of high doses of AGE and SAC given alone or together with CAR caused a significant decrease in serum LDH and CK-MB activities. Further, significant rise in the LDH and CK-MB activities in HTH was noticed in the combined groups of AGE and SAC with CAR. It was also observed that both doses of AGE and SAC significantly increased endogenous antioxidants in HTH. Furthermore, histopathological observations corroborated the biochemical findings. The cytoprotective potential of SAC and AGE were dose-dependent, and SAC was more potent than AGE. The protection offered by aged garlic may be attributed to SAC. Overall, the results indicated that a high dose of AGE and its constituent SAC, when combined with carvedilol, has a synergistic effect in preventing morphological and physiological changes in the myocardium during ISO-induced myocardial damage. 相似文献
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A simple and direct method is described to construct the soliton-like solution for the general KdV equation with external force. Crucial to the method is the assumption that the solution chosen is a special truncated expansion. 相似文献
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Abstract. We formulate a robust optimal stopping-time problem for a state-space system and give the connection between various notions
of lower value function for the associated games (and storage function for the associated dissipative system) with solutions
of the appropriate variational inequality (VI) (the analogue of the Hamilton—Jacobi—Bellman—Isaacs equation for this setting).
We show that the stopping-time rule can be obtained by solving the VI in the viscosity sense and a positive definite supersolution
of the VI can be used for stability analysis. 相似文献
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Abstract This paper develops a bioeconomic forestry model that makes it possible to take ecosystem services that are independent of the age structure of trees into account. We derive the Faustmann–Hartman optimal harvesting strategy as a special case. The bioeconomic model is then extended to account for the fact that forest harvesting decisions impact on other ecological resources, which provide benefits for the wider community. The paper focuses on impacts associated with disturbance caused by logging operations and habitat destruction due to tree removal. This enables us to explore the interactions between forest management and the dynamics of ecological resources. The optimal rotation rule is obtained as a variation on the traditional Faustmann–Hartman equation, where an additional term captures the potential benefits derived from the growth of the ecological resource valued at its shadow price. The steady‐state solutions to the problem and sensitivity to model parameter are identified using numerical analysis. 相似文献
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YCESAN Ahmet~ KEN A.Ceylan Department of Mathematics Süleyman Demirel University Isparta Turkey 《中国科学A辑(英文版)》2008,51(2):233-240
We derive intrinsic formulation for elastic line deformed on a pseudo-hypersurface by an external field in the pseudo-Euclidean spaces E_v~n.This formulation determines elastic line deformed on a pseudo-hypersurface. 相似文献
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Chen Hua Wu Shaohua 《偏微分方程(英文版)》2008,21(1):45-58
We prove the local existence and uniqueness of week solution of the hyperbolic-parabolic Chemotaxis system with some nonlinear product terms. For one dimensional case, we prove also the global existence and uniqueness of the solution for the problem. 相似文献